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AEC-Q100 Digital Isolators

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Image	Part #	Mfr.	Description	Datasheet	Availability	Pricing (EUR) Filter the results in the table by unit price based on your quantity.	Qty.	Series	Mounting Style	Package/Case	Number of Channels	Polarity	Data Rate	Isolation Voltage	Isolation Type	Supply Voltage - Max	Supply Voltage - Min	Operating Supply Current	Propagation Delay Time	Minimum Operating Temperature	Maximum Operating Temperature	Qualification	Packaging
Digital Isolators 1 KV 4-channel digital isolator SI8642BA-B-IUR Skyworks Solutions, Inc. 1: 3,03 € 850In Stock 7.500On Order	Mfr. Part No. SI8642BA-B-IUR Mouser Part No 634-SI8642BA-B-IUR	Skyworks Solutions, Inc.	Digital Isolators 1 KV 4-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	850In Stock 7.500On Order On Order Ship Dates Mfr. No: SI8642BA-B-IUR Stock: 850 Can Dispatch Immediately On Order: 5.000 Expected 1/26/2027 2.500 Expected 2/25/2027 Factory Lead Time: 14 Weeks	Cut Tape 3,03 € 2,28 € 2,09 € 1,88 € Reel 1,62 € View 1,79 € 1,76 € 1,68 € 1,59 € MouseReel Available	Min.: 1 Mult.: 1 : 2.500	Si864x	SMD/SMT	QSOP-16	4 Channel	Unidirectional	150 Mb/s	1000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 2.5 kV 4-channel digital isolator SI8642BB-B-IS Skyworks Solutions, Inc. 1: 3,37 € 1.833In Stock	Mfr. Part No. SI8642BB-B-IS Mouser Part No 634-SI8642BB-B-IS	Skyworks Solutions, Inc.	Digital Isolators 2.5 kV 4-channel digital isolator	Datasheet	1.833In Stock	3,37 € 2,55 € 2,23 € 2,06 € View 1,99 € 1,93 € 1,87 € 1,82 €	Min.: 1 Mult.: 1	Si864x	SMD/SMT	SOIC-Wide-16	4 Channel	Unidirectional	150 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 5 kV 4-channel digital isolator SI8642ED-B-IS Skyworks Solutions, Inc. 1: 3,72 € 1.357In Stock 4.094On Order	Mfr. Part No. SI8642ED-B-IS Mouser Part No 634-SI8642ED-B-IS	Skyworks Solutions, Inc.	Digital Isolators 5 kV 4-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	1.357In Stock 4.094On Order On Order Ship Dates Mfr. No: SI8642ED-B-IS Stock: 1.357 Can Dispatch Immediately On Order: 1.932 Expected 1/21/2027 2.162 Expected 2/11/2027 Factory Lead Time: 14 Weeks	3,72 € 2,83 € 2,48 € 2,30 € View 2,22 € 2,15 € 2,09 € 2,08 € 2,03 €	Min.: 1 Mult.: 1	Si864x	SMD/SMT	SOIC-Wide-16	4 Channel	Unidirectional	150 Mb/s	5000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 5 kV 4-channel digital isolator SI8642ED-B-IS2 Skyworks Solutions, Inc. 1: 3,91 € 1.718In Stock 3.496Expected 1/8/2027	Mfr. Part No. SI8642ED-B-IS2 Mouser Part No 634-SI8642ED-B-IS2	Skyworks Solutions, Inc.	Digital Isolators 5 kV 4-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	1.718In Stock 3.496Expected 1/8/2027	3,91 € 2,95 € 2,61 € 2,54 € 2,11 €	Min.: 1 Mult.: 1	Si864x	SMD/SMT	SOIC-Wide-16	4 Channel	Unidirectional	150 Mb/s	5000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 5 kV 5-channel digital isolator SI8651BD-B-IS Skyworks Solutions, Inc. 1: 4,23 € 2.428In Stock	Mfr. Part No. SI8651BD-B-IS Mouser Part No 634-SI8651BD-B-IS	Skyworks Solutions, Inc.	Digital Isolators 5 kV 5-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	2.428In Stock	4,23 € 3,23 € 2,92 € 2,68 € View 2,55 € 2,48 € 2,44 € 2,41 € Quote	Min.: 1 Mult.: 1	Si865x	SMD/SMT	SOIC-Wide-16	5 Channel	Unidirectional	150 Mb/s	5000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 2.5 kV 5-channel digital isolator SI8652AB-B-IS1R Skyworks Solutions, Inc. 1: 3,63 € 3.589In Stock	Mfr. Part No. SI8652AB-B-IS1R Mouser Part No 634-SI8652AB-B-IS1R	Skyworks Solutions, Inc.	Digital Isolators 2.5 kV 5-channel digital isolator	Datasheet	3.589In Stock	Cut Tape 3,63 € 2,75 € 2,53 € 2,29 € View Reel 1,98 € 2,17 € 2,16 € 2,09 € 1,98 € MouseReel Available	Min.: 1 Mult.: 1 : 2.500	Si865x	SMD/SMT	SOIC-Narrow-16	5 Channel	Unidirectional	1 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.5 V		35 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 2.5 kV 5-channel digital isolator SI8652BB-B-IS1 Skyworks Solutions, Inc. 1: 3,78 € 3.277In Stock	Mfr. Part No. SI8652BB-B-IS1 Mouser Part No 634-SI8652BB-B-IS1	Skyworks Solutions, Inc.	Digital Isolators 2.5 kV 5-channel digital isolator	Datasheet	3.277In Stock	3,78 € 2,87 € 2,51 € 2,33 € View 2,24 € 2,18 € 2,13 € 2,06 €	Min.: 1 Mult.: 1	Si865x	SMD/SMT	SOIC-Narrow-16	5 Channel	Unidirectional	150 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 3.75 kV 5-channel digital isolator SI8652BC-B-IS1R Skyworks Solutions, Inc. 1: 4,19 € 1.970In Stock	Mfr. Part No. SI8652BC-B-IS1R Mouser Part No 634-SI8652BC-B-IS1R	Skyworks Solutions, Inc.	Digital Isolators 3.75 kV 5-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	1.970In Stock	Cut Tape 4,19 € 3,16 € 2,90 € 2,61 € View Reel 2,35 € 2,49 € 2,47 € 2,36 € 2,35 €	Min.: 1 Mult.: 1 : 2.500	Si865x	SMD/SMT	SOIC-Narrow-16	5 Channel	Unidirectional	150 Mb/s	3750 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape
Digital Isolators 5 kV 5-channel digital isolator SI8652BD-B-IS Skyworks Solutions, Inc. 1: 4,29 € 1.213In Stock	Mfr. Part No. SI8652BD-B-IS Mouser Part No 634-SI8652BD-B-IS	Skyworks Solutions, Inc.	Digital Isolators 5 kV 5-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	1.213In Stock	4,29 € 3,27 € 2,92 € 2,69 € View 2,58 € 2,50 € 2,46 € 2,41 € Quote	Min.: 1 Mult.: 1	Si865x	SMD/SMT	SOIC-Wide-16	5 Channel	Unidirectional	150 Mb/s	5000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 1 KV 5-channel digital isolator SI8655BA-B-IUR Skyworks Solutions, Inc. 1: 3,53 € 989In Stock	Mfr. Part No. SI8655BA-B-IUR Mouser Part No 634-SI8655BA-B-IUR	Skyworks Solutions, Inc.	Digital Isolators 1 KV 5-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	989In Stock	Cut Tape 3,53 € 2,67 € 2,45 € 2,21 € View Reel 1,91 € 2,10 € 2,08 € 1,96 € 1,91 €	Min.: 1 Mult.: 1 : 2.500	Si865x	SMD/SMT	QSOP-16	5 Channel	Unidirectional	150 Mb/s	1000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape
Digital Isolators 2 kV 6-channel digital isolator SI8660AB-B-IS1R Skyworks Solutions, Inc. 1: 4,12 € 688In Stock 2.500Expected 1/22/2027	Mfr. Part No. SI8660AB-B-IS1R Mouser Part No 634-SI8660AB-B-IS1R	Skyworks Solutions, Inc.	Digital Isolators 2 kV 6-channel digital isolator	Datasheet	688In Stock 2.500Expected 1/22/2027	Cut Tape 4,12 € 3,10 € 2,86 € 2,57 € Reel 2,49 € View 2,49 € 2,22 € MouseReel Available	Min.: 1 Mult.: 1 : 2.500	Si86xx	SMD/SMT	SOIC-Narrow-16	6 Channel	Unidirectional	1 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.5 V		35 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 2.5 kV 6-channel digital isolator SI8660BB-B-IS1 Skyworks Solutions, Inc. 1: 4,32 € 3.396In Stock 8.256Expected 1/22/2027	Mfr. Part No. SI8660BB-B-IS1 Mouser Part No 634-SI8660BB-B-IS1	Skyworks Solutions, Inc.	Digital Isolators 2.5 kV 6-channel digital isolator	Datasheet	3.396In Stock 8.256Expected 1/22/2027	4,32 € 3,29 € 2,89 € 2,68 € View 2,59 € 2,52 € 2,46 € 2,38 €	Min.: 1 Mult.: 1	Si866x	SMD/SMT	SOIC-Narrow-16	6 Channel	Unidirectional	150 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 3.75 kV 6-channel digital isolator SI8660BC-B-IS1R Skyworks Solutions, Inc. 1: 4,56 € 2.041In Stock	Mfr. Part No. SI8660BC-B-IS1R Mouser Part No 634-SI8660BC-B-IS1R	Skyworks Solutions, Inc.	Digital Isolators 3.75 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	2.041In Stock	Cut Tape 4,56 € 3,47 € 3,20 € 2,90 € View Reel 2,61 € 2,76 € 2,67 € 2,64 € 2,61 € MouseReel Available	Min.: 1 Mult.: 1 : 2.500	Si866x	SMD/SMT	SOIC-Narrow-16	6 Channel	Unidirectional	150 Mb/s	3750 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 5 kV 6-channel digital isolator SI8660BD-B-IS Skyworks Solutions, Inc. 1: 4,96 € 1.270In Stock 3.312Expected 2/25/2027	Mfr. Part No. SI8660BD-B-IS Mouser Part No 634-SI8660BD-B-IS	Skyworks Solutions, Inc.	Digital Isolators 5 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	1.270In Stock 3.312Expected 2/25/2027	4,96 € 3,78 € 3,37 € 3,14 € View 3,00 € 2,92 € 2,86 € 2,80 €	Min.: 1 Mult.: 1	Si866x	SMD/SMT	SOIC-Wide-16	6 Channel	Unidirectional	150 Mb/s	5000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 5 kV 6-channel digital isolator SI8660BD-B-ISR Skyworks Solutions, Inc. 1: 4,96 € 1.247In Stock 1.250Expected 12/11/2026	Mfr. Part No. SI8660BD-B-ISR Mouser Part No 634-SI8660BD-B-ISR	Skyworks Solutions, Inc.	Digital Isolators 5 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	1.247In Stock 1.250Expected 12/11/2026	Cut Tape 4,96 € 3,78 € 3,49 € 3,17 € Reel 2,92 € View 3,03 € 2,98 € 2,86 € Quote MouseReel Available	Min.: 1 Mult.: 1 : 1.250	Si866x	SMD/SMT	SOIC-Wide-16	6 Channel	Unidirectional	150 Mb/s	5000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 2.5 kV 6-channel digital isolator SI8661BB-B-IUR Skyworks Solutions, Inc. 1: 4,45 € 1.358In Stock 2.500Expected 2/25/2027	Mfr. Part No. SI8661BB-B-IUR Mouser Part No 634-SI8661BB-B-IUR	Skyworks Solutions, Inc.	Digital Isolators 2.5 kV 6-channel digital isolator	Datasheet	1.358In Stock 2.500Expected 2/25/2027	Cut Tape 4,45 € 3,35 € 3,09 € 2,79 € View Reel 2,31 € 2,64 € 2,62 € 2,47 € 2,31 € MouseReel Available	Min.: 1 Mult.: 1 : 2.500	Si866x	SMD/SMT	QSOP-16	6 Channel	Unidirectional	150 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 3.75 kV 6-channel digital isolator SI8661BC-B-IS1 Skyworks Solutions, Inc. 1: 4,56 € 2.059In Stock	Mfr. Part No. SI8661BC-B-IS1 Mouser Part No 634-SI8661BC-B-IS1	Skyworks Solutions, Inc.	Digital Isolators 3.75 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	2.059In Stock	4,56 € 3,47 € 3,20 € 2,90 € View 2,76 € 2,67 € 2,64 € 2,61 €	Min.: 1 Mult.: 1	Si866x	SMD/SMT	SOIC-Narrow-16	6 Channel	Unidirectional	150 Mb/s	3750 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 5 kV 6-channel digital isolator SI8661BD-B-IS Skyworks Solutions, Inc. 1: 5,09 € 1.544In Stock	Mfr. Part No. SI8661BD-B-IS Mouser Part No 634-SI8661BD-B-IS	Skyworks Solutions, Inc.	Digital Isolators 5 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	1.544In Stock	5,09 € 3,89 € 3,51 € 3,22 € View 3,08 € 2,99 € 2,93 € 2,88 €	Min.: 1 Mult.: 1	Si866x	SMD/SMT	SOIC-Wide-16	6 Channel	Unidirectional	150 Mb/s	5000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 2.5 kV 6-channel digital isolator SI8662EB-B-IU Skyworks Solutions, Inc. 1: 4,32 € 2.476In Stock 10.656On Order	Mfr. Part No. SI8662EB-B-IU Mouser Part No 634-SI8662EB-B-IU	Skyworks Solutions, Inc.	Digital Isolators 2.5 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	2.476In Stock 10.656On Order On Order Ship Dates Mfr. No: SI8662EB-B-IU Stock: 2.476 Can Dispatch Immediately On Order: 2.112 Expected 11/12/2026 8.544 Expected 4/12/2027 Factory Lead Time: 14 Weeks	4,32 € 3,29 € 2,76 € 2,64 € View 2,59 € 2,51 € 2,45 € 2,44 € Quote	Min.: 1 Mult.: 1	Si866x	SMD/SMT	QSOP-16	6 Channel	Unidirectional	150 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 3.75 kV 6-channel digital isolator SI8662EC-B-IS1 Skyworks Solutions, Inc. 1: 4,62 € 807In Stock 1.152Expected 1/28/2027	Mfr. Part No. SI8662EC-B-IS1 Mouser Part No 634-SI8662EC-B-IS1	Skyworks Solutions, Inc.	Digital Isolators 3.75 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	807In Stock 1.152Expected 1/28/2027	4,62 € 3,52 € 3,13 € 2,91 € View 2,79 € 2,70 € 2,66 € 2,60 €	Min.: 1 Mult.: 1	Si866x	SMD/SMT	SOIC-Narrow-16	6 Channel	Unidirectional	150 Mb/s	3750 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 3.75 kV 6-channel digital isolator SI8662EC-B-IS1R Skyworks Solutions, Inc. 1: 4,57 € 3.735In Stock 5.000Expected 1/8/2027	Mfr. Part No. SI8662EC-B-IS1R Mouser Part No 634-SI8662EC-B-IS1R	Skyworks Solutions, Inc.	Digital Isolators 3.75 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	3.735In Stock 5.000Expected 1/8/2027	Cut Tape 4,57 € 3,48 € 3,21 € 2,91 € View Reel 2,60 € 2,77 € 2,68 € 2,65 € 2,60 € MouseReel Available	Min.: 1 Mult.: 1 : 2.500	Si866x	SMD/SMT	SOIC-Narrow-16	6 Channel	Unidirectional	150 Mb/s	3750 Vrms	Capacitive Coupling	5.5 V	2.5 V	5.6 mA, 7.5 mA	8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 5 kV 6-channel digital isolator SI8662ED-B-ISR Skyworks Solutions, Inc. 1: 4,86 € 924In Stock	Mfr. Part No. SI8662ED-B-ISR Mouser Part No 634-SI8662ED-B-ISR	Skyworks Solutions, Inc.	Digital Isolators 5 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	924In Stock	Cut Tape 4,86 € 3,74 € 3,46 € 3,14 € Reel 2,86 € View 2,98 € 2,89 € 2,80 € MouseReel Available	Min.: 1 Mult.: 1 : 1.250	Si866x	SMD/SMT	SOIC-Wide-16	6 Channel	Unidirectional	150 Mb/s	5000 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 2.5 kV 6-channel digital isolator SI8663BB-B-IU Skyworks Solutions, Inc. 1: 4,32 € 3.950In Stock 14.880On Order	Mfr. Part No. SI8663BB-B-IU Mouser Part No 634-SI8663BB-B-IU	Skyworks Solutions, Inc.	Digital Isolators 2.5 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	3.950In Stock 14.880On Order On Order Ship Dates Mfr. No: SI8663BB-B-IU Stock: 3.950 Can Dispatch Immediately On Order: 4.416 Expected 11/17/2026 10.464 Expected 1/28/2027 Factory Lead Time: 14 Weeks	4,32 € 3,29 € 2,76 € 2,64 € View 2,59 € 2,51 € 2,45 € 2,44 € Quote	Min.: 1 Mult.: 1	Si866x	SMD/SMT	QSOP-16	6 Channel	Unidirectional	150 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube
Digital Isolators 2.5 kV 6-channel digital isolator SI8663BB-B-IUR Skyworks Solutions, Inc. 1: 4,45 € 4.384In Stock 22.500On Order	Mfr. Part No. SI8663BB-B-IUR Mouser Part No 634-SI8663BB-B-IUR	Skyworks Solutions, Inc.	Digital Isolators 2.5 kV 6-channel digital isolator	Datasheet	4.384In Stock 22.500On Order On Order Ship Dates Mfr. No: SI8663BB-B-IUR Stock: 4.384 Can Dispatch Immediately On Order: 12.500 Expected 1/21/2027 10.000 Expected 3/11/2027 Factory Lead Time: 14 Weeks	Cut Tape 4,45 € 3,35 € 3,09 € 2,79 € View Reel 2,31 € 2,64 € 2,62 € 2,47 € 2,31 € MouseReel Available	Min.: 1 Mult.: 1 : 2.500	Si866x	SMD/SMT	QSOP-16	6 Channel	Unidirectional	150 Mb/s	2500 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Reel, Cut Tape, MouseReel
Digital Isolators 3.75 kV 6-channel digital isolator SI8663BC-B-IS1 Skyworks Solutions, Inc. 1: 4,62 € 904In Stock 1.344Expected 12/3/2026	Mfr. Part No. SI8663BC-B-IS1 Mouser Part No 634-SI8663BC-B-IS1	Skyworks Solutions, Inc.	Digital Isolators 3.75 kV 6-channel digital isolator Learn More about Skyworks Solutions, Inc. siliconlabssi86x	Datasheet	904In Stock 1.344Expected 12/3/2026	4,62 € 3,52 € 3,13 € 2,91 € View 2,79 € 2,70 € 2,66 € 2,60 €	Min.: 1 Mult.: 1	Si866x	SMD/SMT	SOIC-Narrow-16	6 Channel	Unidirectional	150 Mb/s	3750 Vrms	Capacitive Coupling	5.5 V	2.375 V		8 ns	- 40 C	+ 125 C	AEC-Q100	Tube